[P]DAONIL 5 MG TABLETS

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How should Daonil be taken?
You should take your Daonil tablets 5mg swallowed whole with a glass of water just before breakfast of if you only have a light breakfast, then take your Daonil tablets just before your midday meal. It is important that you do not skip a meal while taking Daonil tablets 5mg. The dose you take depends on how well you respond and your doctor may increase your dose until your blood glucose has reached normal levels and remains controlled. You should continue to take your Daonil tablets 5mg for as long as recommended by your doctor, as they with help maintain your blood sugar levels but will not cure your diabetes.
How long should you take Daonil?
You should continue to take your Daonil tablets 5mg for as long as recommended by your doctor, as they with help maintain your blood sugar levels but will not cure your diabetes.
Missed dose of Daonil
If you miss a dose of Daonil tablets 5mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Daonil be stored?
You should store your Daonil tablets 5mg below 25°C in a cool dry place.

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SKU

003863

LKR4.35 Per Tablet/Capsule

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What is Daonil used for?
Daonil tablets 5mg are an oral diabetes medication used to control blood sugar levels in people with mild to moderate type-2 diabetes mellitus (also called non insulin-dependent diabetes or maturity onset diabetes) who are unable to achieve adequate glycaemic control (normal blood sugar levels) with diet and exercise alone. Daonil tablets 5mg can be used alone as monotherapy, in conjunction with diet and exercise, or in combination with other antihyperglycaemic medication (lowers blood sugar), like metformin, when a single drug does not provide adequate glycaemic control. If Daonil tablets 5mg become less effective, they can be given together with insulin. Diabetes increases the risk of serious health complications, including diabetic retinopathy (damage to the retina in the eye with loss of vision), diabetic neuropathy (nerve damage) and diabetic nephropathy (kidney damage). Maintaining glycaemic control with Daonil tablets 5mg reduces the risk of developing these vascular complications.
How does Daonil work?
Daonil tablets 5mg contain glibenclamide, an oral antihyperglycaemic medication belonging to the sulphonylurea group of drugs. Glibenclamide in Daonil tablets 5mg controls blood glucose (sugar) primarily by acting directly on the beta cells, which are the insulin-producing cells of pancreatic islet tissue, to increase their sensitivity to glucose and to stimulate the cells to produce and release more insulin. Insulin is normally produced in response to food and increased blood glucose levels and it controls postprandial (after eating) blood glucose levels (glycaemic control). In diabetes, resistance to insulin results in loss of glycaemic control. Glibenclamide in Daonil tablets 5mg helps the body to produce sufficient insulin to maintain normal blood glucose levels after a meal as well as between meals and is effective for up to 24 hours. It is thought that as well as acting as an insulin secretagogue (stimulates insulin secretion) glibenclamide in Daonil tablets 5mg also acts on insulin-responsive cells in the liver, muscle and fat cells to increase the number of receptors, which means that insulin control of glucose production by the liver and uptake of insulin into peripheral tissues for energy and storage, is more efficient.

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